Isolation and characterization of triterpenoids from bark of Syzygium alternifolium (Wight) Walp

Natural products from medicinal plants, either as pure phytoconstituents or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. In the present investigation include the extraction, isolation and characterization of active compounds from Syzygium alternifolium (Wight) Walp. Isolated phytoconstituents were forwarded to phytochemical screening and chromatographic techniques such as Thin Layer Chromatography (TLC). Crude bark extract of Syzygium alternifolium was extracted and forwarded to preliminary phytochemical investigation which shows the presence of alkaloids, glycosides, terpenoids, steroids, flavonoids, volatile oils, tannins, proteins and carbohydrates. Based on extractive value, methanolic extract was fractionated with hexane and ethyl acetate. The hexane fraction of methanolic extract was forwarded to column for isolation. Three triterpenoids and sterol, which were isolated and characterized by chromatographical and spectroscopical analysis as friedelane, friedelin 3â-friedelinol and stigmasterol, respectively.